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KMID : 1037520160320040186
Vascular Specialist International
2016 Volume.32 No. 4 p.186 ~ p.189
Successful Anticoagulation Therapy for Antiphospholipid Syndrome with Mobile Aortic Thrombi
Park Hyun-Oh

Moon Seong-Ho
Kim Jong-Woo
Byun Joung-Hun
Kim Sung-Hwan
Yang Jun-Ho
Lee Chung-Eun
Kim Jong-Duk
Abstract
Hypercoagulable states have been associated with aortic thrombosis. Antiphospholipid syndrome (APS) is one of the commonest types of acquired thrombophilia. We report the case of successful anticoagulation management in an APS patient with mobile thrombi within the aorta. A 58-year-old male patient presented to the emergency department (ED) with right-sided hemiparesis. His first symptoms were noted approximately 12?16 hours before presentation to the ED. Magnetic resonance imaging of the brain showed acute embolic infarction of the left frontal and parietotemporal lobes. Transesophageal echocardiography (TEE) and computed tomography angiography (CTA) demonstrated mobile thrombi attached to the wall of the ascending aorta and aortic arch. The patient was diagnosed with APS based on positivity of anti-beta-2 glycoprotein 1 antibodies, and was initiated on anticoagulation therapy. Repeated TEE and CTA revealed complete resolution of the thrombi after 12 days of treatment; the patient was discharged well.
KEYWORD
Aorta, Thrombosis, Antiphospholipid syndrome
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